General Cell Lines and Cell Cultures
Measles virus strain Edmonston (ATCC VR-24™)
Measles virus strain Edmonston (ATCC VR-24™) is a whole-genome sequenced prototype strain isolated in 1954 from a human patient in Massachusetts. Propagated in MRC-5 cells, it is used in respiratory and infectious disease research.
Recommended companion products:
MRC-5 cells (Fisher Cat. No. 50-238-3231, ATCC CCL-171™)
EMEM (Fisher Cat. No. 50-238-2632, ATCC 30-2003™)
Fetal bovine serum (Fisher Cat. No. 50-238-3771, ATCC 30-2020™).
ACROBiosystems HEK293/Human EpCAM Stable Cell Line
EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy.Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.
Biochain Institute Inc FDA Standard Tissue Array, 1; slides/PK
BioChain provides FDA Standard Frozen Tissue Array (TMA) which is designed in conformance with FDA guideline and meeting the requirements for IHC (Immunohistochemistry) and IVD (In vitro Diagnostic Devices) certification. This tissue array has two slides which contain 30 different human normal tissue types and 3 donors per tissue type. It also contains the 41 most popular human tumor tissue samples.
Cayman Chemical Glucagon RECPTR ntagonIst
A competitive antagonist of GCGR (IC50 = 181 nM); blocks glucagon-induced glycogenolysis in primary human hepatocytes, isolated liver, and humanized mice
Cayman Chemical al-trns RetInal 100mg
A natural retinoid that associates with CRBP-I and CRBP-II (Kds = 50 and 90 nM, respectively), which are involved in the intracellular transport of retinol; an intermediate of the phototransduction pathway of photoreceptors; can form toxic conjugates with proteins and lipids, leading to degeneration of the retina
ATCC Genomic RNA from; SARS-CoV-2; variant B.1.1.7
Genomic RNA isolated from a preparation of Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) isolate USA/CA_CDC_5574/2020. This product can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
ATCC ES-D3 (D3); Stem Cell; Mouse (Mus muscullus)
ES-D3 [D3] is an embryonic multipotent stem cell line that was isolated from the embryo of a mouse. This cell line was deposited by T Doetschman and can be used in stem cell research.
ILEX LIFE SCIENCES LLC EMEM FIBROBLASTS 6 X 500 ML
PAN-Biotech EMEM Cell Culture Medium for Fibroblasts, w/o: L-Glutamine, w: 2.2 g/L NaHCO3 (6 x 500 ml). BICARBONATE: With 2.2 g/L Sodium Bicarbonate. GLUCOSE: With glucose. GLUTAMINE: Without glutamine. PHENOL RED: With Phenol Red. STERILE: Yes. STORAGE TEMP: +2-8°C. MANUFACTURER: PAN-Biotech GmbH. COUNTRY OF ORIGIN: Germany. DESCRIPTION: EMEM Fibroblasts is a cell culture medium based on MEM Eagle (Eagle's Minimum Essential Medium) which was in turn developed from BME (Basal Medium Eagle). EMEM Fibroblasts is optimized specifically for the cultivation of fibroblasts. EMEM Fibroblasts is based on EMEM supplemented with additional or higher amount of amino acids and vitamins and is thus optimized for improved growth of fibroblasts. For cultivation of fibroblasts, this medium must be supplemented with 10% FBS before use.
ATCC Non-Enzymatic Cell Dissociation Media, 1X, 100 ML
Trypsin is the most commonly used enzyme for harvesting cells in culture. A non-enzymatic approach is needed when non-protein and animal-component free materials are required. ATCC Non-Enzymatic Cell Dissociation Solution is a sterile, phenol-red free solution composed of a proprietary mixture of chelators representing an optimized alternative to protein-digesting enzymes. This product is totally free of animal-derived components. This product has applications for cell culture, cell growth, and viability.
Eurofins Discoverx PathHunter CHO-K1 AGTRL1 β-Arrestin-1 Cell Line, 2 vials. (93-1050C2)
The PathHunter AGTRL1 (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of AGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AGTRL1 and EA-tagged β-Arrestin-1. Activation of AGTRL1 stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 HTR1A Gi Cell Line, 2 vials. (95-0132C2)
The cAMP Hunter HTR1A Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin/5-HT) based activation of HTR1A GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HTR1A, a naturally Gi/Go coupled GPCR. Upon activation of HTR1A, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 mGLP1R β-Arrestin Cell Line, 2 vials. (93-0478C2)
The PathHunter mGLP1R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. exendin-4) based activation of mGLP1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mGLP1R and EA-tagged β-Arrestin-2. Activation of mGLP1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC SK-N-DZ; Neuroblastoma; Human
SK-N-DZ are neuroblasts that were isolated from the brain of a 2-year-old, White female patient with neuroblastoma. It has applications in immunology and neuroscience.
ATCC Vesicular stomatitis virus; Strain: Indiana Lab
Vesicular stomatitis virus strain Indiana Lab was derived by adaptation of in vivo culture product ATCC VR-1238 to BHK-21 [C-13] cells (ATCC CCL-10). ATCC VR-1238 was propagated in suckling mice and passaged in Guinea pigs and chicken embryos.